This is a must read book. More than a century later, the situation is identical. Several studies indicate that CoQ10 may also have a role in the treatment of essential hypertension. It is not necessary to make up for the amount that was vomited. So can the amino acid glutamine, which is a substitute for glucose in cells.
Why elimination of the symptom is NOT the same as elimination of the disease
Rose I have been taking MSM since I think you are right.. It helps so much with joint pain too. It also makes hair grow, skin softer and vision better. Several things not mentioned here is that since MSM makes cell walls more permeable, all your supplements absorb better if taken with MSM. Also very important NOT to take at night because it gives energy and will keep you awake. I am a believer in this miracle supplement. I cannot believe it! I was living a life on pain killers that were not working and there were even times when I felt as though I wanted to take my life due to the constant state of pain that I was living in.
I can pretty much say, thanks to my best friend recommending MSM, she and it virtually have saved my life! I have wanted to try MSM. I do have some joint issues but also have heard it is wonderful for post menopausal women with skin, hair loss, and nails. I also read somewhere there is a difference processing. Not to get crystallization. Any thoughts on that? Hello, for 2 years now, am suffering from skin condition.
My face is covered with dark patches. It all started on my nose and gradually spread all over the face. I used to have a fair complexion in the past. Pigmanorm cream given to my by the hospital made my skin worst.
Will MSM help in getting a clear skin without dark patches? Reshma, thank you so much for the question. And thank you even more for sharing a bit of your struggle with me. MSM would be a small piece of the puzzle, but you need to heal your skin from the inside out. The doc says its partly a scar tissue and partly hyperpigmentation. Would MSM help me in this? Im already using Alevera fresh pulp on it. But no improvement in color so far.
Please help me in this. I am male age 33 I am suffered by pigmentation from last five years I consult lot doctors. IPL leaser but no change please sir give good suggestion. And I also piles and back problem disc. I have RA that is in a horrible flare and have heard wonderful things about it. Emily, tremendous admiration for you. I have just bought MSM powder and look forward to start on it today. I have strong weakness for coffee, oats and bread. I have also bought MSM cream to apply.
I just hope to see improvements soon.. Life has not been the same since eczema struck me. This is definitely worth trying, I wish I had sooner! I just found your site and I have been taking MSM for about two to three weeks. Please, if you have a minute, lead me in the right direction so that I know If mine is ok for now… Thank you for your time and cooperation concerning this matter.
Orlando, the Sunfood brand is just fine. As long as it resonates with your unique metabolism, keep it up! I have been talking msm for a month now.
The reality is, shoring up your nutrient deficiencies will help alleviate a lot of symptoms, but you need to make sure that your overall nutrition and lifestyle are up to par as well. Tons of info and free resources for you in my show archives: My teenage son has a host of problems chronic daily migraine headaches, fatty liver disease, high bp, autistic, etc.
Are MSM capsules or pills okay or do I need to increase the dose due to absorption issues related to capsules? Thank You Shawn For this Information. I need it for Joint and weight Lost. Hi shawn, first of all thank you for an amazing site, My name is Elzabeth, I am a health conscious type since I was diagnose with H.
I have been searching on internet to find natural cure, it is impossible. I have tried different things ,for egg fish oil, garlic pils, oils and vitamins. They have an affect of lowering it a bit. I am tired of using medication , I have tried different High Blood medication but it does not work for me , the side effect is a lot. Do you know or have an idea if using SMS will have any positive affect. Does MSM help with neuropathy pain numbness and tingling in legs? Burning and pins and needles sensation in feet?
Also, will MSM help with osteoarthritis? If I am allergic to sulfate in some antibiotics, should I be concerned about the sulfur in this product? Hello everyone , just wanted to say how much MSM has helped me.
I have been suffering from chronic Gastroparesis caused by a pinched vagus nerve that basically got mangled between masses of twisted muscular scar tissue from severe neck muscular tears. And I basically lived the last 18 years in excruciating pain unable to eat or go to the bathroom regularly , and thinking each day would be my last, but I began taking opti MSM from Kala Health bergstrom nutraceuticals available on Amazon. And I noticed the muscles which were all hard as rock began releasing , little by little, and my digestion started coming back!.
I would like to try msm for stronger muscles ligaments and tendons, because I strain due to age, but I do not want to lose any weight I welcome your comments. So I dont know if im still having detox symptoms or if its just a normal reaction to too much MSM.. Seth be sure to take vitamin c with it. For 4 grams msm, take 2 grams vitamin c. Is it 2 much meds? I have arthritis real baaaaad.
My doc perscrib dicflonec scarrrrry drug, I refuse 2 take it, also on deppression meds Zoloft. I am very interested in any ideas of how to incorporate this miracle supplement into my regime. They say to add it in the bath water so am going to do this but was wondering if I will still get the same benefits and if so how many baths will I need to do.
Would love to be a remission story in my cancer journey Thanks Rita. I have never experienced a single supplement with all the benefits. I take two MG daily some days three. I have just ordered MSM after reading your site. I have polymyalgia, did not want to take the steroids the doctor prescribed, so have to deal with the pain all day.
Before this, was very active with tennis and golf. Have been slow walking a mile a day to try and stay a little supple, but pretty painful. Will let you know how I get on with MSM in my body! I suffer with lots of muscle stiffness ,soreness and strains. Also would like something to improve my digestion, constipation and PMS. Will it help the above problems??? Does it do anything for sugar and general food cravings??? Hello Shawn, thanks for being this good.
Is it safe for one with type 2 diabetes to take msm? So, if I choose to take like 6 capsules daily, instead of the suggested 3, will I have issues with the magnesium stearate contents? Hi Shown, is it safe for me to take msm, if i have type 2 diabetes? Dear Shawn, thank you for your very helpful website. I just ordered MSM powder, mainly to help with constipation and thinning hair. Could you tell me how much powder I should start with? If any one can answer that question for me it would be great thank you so much my husband has glaucoma eye pressure is high can msm works none of the medications is taking works.
I suffer with the occasional cold sore. Can I use it externally as well, by making a paste out of it? I am forever grateful for just the thought, thank you. Kody, I want to thank you first of all for caring so much about your grandmother and asking questions.
Sometimes the best thing for us is to simply have someone who cares deeply for us. It would be way cheaper to buy a big bottle of Drano. At least some of them have the same active ingredient. Your bones are being constantly remodeled in response to the stresses or lack thereof placed on them.
Osteoclasts tear down some bone here, while osteoblasts will build some more over there. Also, to the person whose acne resolved when the alkalizing pump was installed and he had to drink the tap water…. This would be a more likely factor for that change.
The sad part here is, this person clearly needs psychological medication, but is highly unlikely to seek help, or be talked into help because the condition prevents treatment…. I have a friend that is a doctor. Now we all know that a doctor can be wrong on an diagnoses. Now when they tell you about something that they learned in Med School, well that is different. Those of you who want to comment on his conspiracy.
Well you are falling under a lie at this very moment. Also think who is going to pay the money to buy these supplements, Us!
Or should we believe the doctors. Whole food is not a supplement. But go ahead, fill your face with burgers, fries, cakes etc.. You know the classic America diet stuff. I have a Doctor friend. I got caught up in this mass delusion. I spent way to much money. Then he enlightened me with the truth. That elusive thing the truth and it did set me free. They have the ability to keep our blood PH at just above 7. I know that eating healthy is important. As far as test strips go, you are urinating excess acidity in the blood because that is how we get ride of it.
So it is going to be more acidic. So I think I would trust the doctors. They have nothing to gain from lying. Although this growing industry has plenty to benefit from eluding the truth.
Which most have already contributed too. So for those who want to think someone is delusional. I think those who have fallen for this scam and spent money on this. Oh wait maybe his blood is too acidic. Yes, your kidneys filter your blood getting rid of excess acidity or whatever else there may be in your blood. With the current American diet acid forming foods are eaten in excess, creating a never ending cycle of slightly acidic blood.
Thus Low Grade Chronic Acidosis. How long when your blood increases is acidity does it take for your kidneys to get rid of the excess? Therefore eating healthy and alkaline forming foods to keep your blood in the optimal PH range, not putting as much pressure on your kidneys etc… Is a good thing.
No matter how you look at it. I teach physiology and therefore I believe that I know a little bit about how the body works. Let me try to dispel some of the erroneous notions you have about how kidney functions to maintain the pH balance and also explain how well the pH is maintained by the body utilizing the blood buffer system.
The ability of our body to maintain the physiological parameters within a very tight range is called homeostasis. As for pH, the body maintains a pH between 7. Blood pH is primarily maintained by a buffer system called the bicarbonate buffer system. The bicarbonate system has the ability to move the reaction backward and forward mediated by an amazing enzyme called carbonic anhydrase.
It is the amount of protons that determine the pH. The capture and release of protons is mediated by the carbonic anhydrase enzyme. These reactions happen in microseconds because excess protons can be harmful. Your contention that urine is acidic because of excess acid in blood is not true. The excess protons produced as a result of metabolic activity is immediately neutralized in the blood by the bicarbonate buffer system.
What the kidney does is to remove the excess protons bound to bicarbonate. In the same way, if blood pH turns slightly alkaline, the bicarbonate buffer can release bound protons to bring the pH back into the physiological range.
The physiological pH does not usually go beyond the set range in healthy individuals. Blood acidosis and alkalosis occur due to diseases. Food alone will not contribute to the change in pH beyond the normal range.
Therefore, as for the alkaline diet, I am not convinced that the diet will influence blood pH in any significant way. Trust in the ability of your body and eat healthy. As someone else mentioned in the thread here, if you see any industry resorting to scare tactics to drive their business, your skepticism antenna should go up immediately.
You are really talking about excessive oxidative damage. Even emotional stress does this. Eat foods that help support metabolic pathways and reduce oxidative damage. All this talk about pH is nonsense. The reason vaginal yeast and gut Candida over grow is due to lowered immune function. Destress, get good sleep, eat a variety of whole foods and move your lymphatic exercise. Telling people which nuts or fruits or meats are better than the other is ridiculous.
Telling people to drink anything other than filtered mineralized water is bogus. The biggest tell tale sign of this scam is how they use scare tactic. But they can help you with all your health ailments with just a few drops of this magic alkaline drop.
Sounds like those traveling wagon salesmen. Please search opposing arguments so you can really make an educated decision. Just to clarify a thought process you seem to fall on often: In the end, a good doctor will tell you no doctor knows your body better than you. Yes, a good doctor will tell someone that they can describe their symptoms best and know when something may be amiss…sort of. Regular laypeople have no real understanding of medicine or science. If you are somewhat knowledgeable, educated, intelligent, you can get some information from research and some from doctors…but if you have no basic education about how your body works, and you are consulting sources that are basically lies held together with bandwidth and duct tape, then you are going to end up drawing flawed conclusions.
Eat all the veggies and fruits you want to; they are seriously healthy for you. This is not because they are alkaline or change the alkalinity of your blood. Your body can handle hard water alkaline — usually above 8.
It can handle soft water acid — lower than about 6. So you can drink all the alkaline water you want to; the body is going to attempt to keep the blood at 7.
I think it has been established firmly that diet does effect urinary pH, due to the bi-products of certain foods…. How do these bi-products get to the kidneys??? Although the shift in blood pH is negligible and short a lifetime of these microadjustments can have serious consequences!
Nobody believes one glass of milk will give you osteoporosis, but an acid-based diet of animal products and processed food certainly might, and there is a significant amount of data that would point to this. And where is the evidence that food alters blood pH? In fact urinary pH can be altered by by things other than diet. Even though ALL foods metabolize in to acids this does not mean diet will change blood pH either.
So you think the holistic medical industry is the Satanic cancer industry since I have been working in holistic medicine for decades? I find this alarming and am scared after reading the negative aspects of acidic blood…. What is a person to do then?!?!? If you had a blood pH of 5 you would be dead. Normal blood pH is 7.
Anything slightly out of that range and you would be very ill. Anything more out of range such as a pH of 6 or 8 and you would be on your death bed if not already dead. You need to double check your lab report and see what they were testing the pH of. If it does say blood then there is a major lab error or you are a true zombie. James, I hope you are doing well. I was away for some time but it is a pleasure to see you in admirable perseverance. James, you were definitely correct. My doctors response was exactly the same as yours: What is the net effect of the body working hard to maintain blood Ph levels when it encounters a constant barrage of acidic foods.
My body is pretty good at maintaining my blood sugar levels but that does not make it immune to the damage done carrying out this process.
ALL foods are acid forming. Many of the so-called alkaline foods actually have acidic pH levels to begin with mostly due to beneficial acids. And again, ALL foods get metabolized in to acids. There is NO such thing as an alkaline forming food. The so-called alkaline diet is a myth.
Only if you want to ruin your health. When ingested it is neutralized by the stomach acid forming carbonic acid and sodium chloride salt. So it does not even make it past the stomach acid. If an excess of sodium chloride is formed then hyperchloremic acidosis can result. As for ingesting baking soda this can lead to all sorts of health issues including cancer and heart disease. Read this thread for a more detailed explanation:.
You guys have to take a look at this study: First of all note how they say hypothesized. A hpothesis is an educated guess not backed by any real evidence. Secondly they mention the product used by name, which leads me to believe that the study may have been funded by the manufacturer, which would mean a conflict of interest.
For example, did all of the 82 patients have exactly the same 0. So where is this supposed latent acidosis they are referring to? Magnesium acts like a natural calcium channel blocker thus relaxing blood vessels and increasing circulation that aids with healing. Just start listening to your body…. There are certain foods that really work for me and others not so much. Take the time to listen to your needs and not as much about what others are telling you to do? And what if you are a sugar addict?
If your body says I want sugar are you going to load up on ice cream? People often assume they need things based on cravings because the average person does not have the faintest clue how the body really works. Same reason so many people fell for the alkalize for health myth. Or the ingesting baking kills cancer cells myth. Or the parasites cause all cancer and AIDS myth……….
Natural magnesium sourced from foods is what you are all really looking for. Nothing much works in the body without it like calcium absorption cannot occur without enough magnesium. I think with the right amount of Mg not supplements our pH levels will always be normal! Thank you for being able to finally provide me with a very good explanation to the importance of Magnesium.
I have been taking chemo therapy for the past 4. Magnesium is essential to many things. In fact about processes in the body. But it is a calcium antagonist, which is why it works like a natural calcium channel blocker and is used for things like preventing migraines and calcium induced high blood pressure.
Calcium absorption itself is actually dependent on silica and vitamin D, which aid in the absorption. Deposition of calcium and other minerals in the bones is also dependent on silica. Calcium loss from bones is most often due to hyperparathyroidism from benign tumors or pseudohyperparathyroidism from excess phosphorus intake.
A lack of silica or exercise can also lead to mineral loss from bones. And none of the forms of arthritis are from a lack of magnesium. Arthritis actually means inflammation of the joint, not calcium deposition. Bone spurs osteophytes can occur in some cases of arthritis, but this is not from a lack of magnesium.
Osteophytes, which contain various mineral including calcium and magnesium, are formed from pressure on the bone. In arthritis from bones putting pressure on each other and in other cases from pulling of tendons on bone. Finally, magnesium does not regulate our pH. As pointed out previously our pH is regulated almost exclusively by respiration and kidney function. As for magnesium supplementation there are different forms of magnesium.
The most often used is magnesium oxide because it is the cheapest for manufacturers to use. But the stuff is crap!!!! Magnesium oxide in water forms a caustic magnesium hydroxide. Same as Milk of Magnesia. It is very poorly absorbed, can adversely neutralize stomach acid leading to numerous health problems and is hard on the tissues due to its mildly caustic nature. I prefer acidified forms of magnesium.
Magnesium malate is my first choice followed by magnesium citrate. First intelligent comment on this post… and that James person surely has a very fulfilling life. Paying attention to your body and using common sense, if you feel some tomato craving, go for it.
Very interesting about the acid-bone connection. While it has always seemed logical that calcium from bone would be used as buffer, your article shed new light that makes me question this logic. Bones are only used as a buffer as a very last resort. This would require long term and extreme acidosis to break the bones down to any significance. Acidosis this bad is so rare that most doctors will never see such as case in their entire lives.
On the other hand some bone cells do secrete citric acid to break down old bone for the bone remoldeling process. But this is a good thing as it is essential to maintaining healthy bone. I think there are more people that try to feed false info than you think and they start like this….. I had a child die needing five major organ transplants. She was born in both liver and renal failure. She spent her life battling acidosis. Trust me, if you were truly acidotic from your diet and what you eat, you would not be bopping to the store frequently to buy fresh produce to make your green smoothies!!!
You would be sick in bed wishing death would just get it over with already!!! People who spread this bunk lack any basic comprehension of how the biochemistry of the body works. For one thing, the ph in your stomach thanks to hcl, kcl, NaCl is so caustically high…. You cannot humanly consume anything remotely close to those ph levels bc of the deeply painful burns and damage it causes in your mouth, throat, and esophagus.
This is Why the stomach has a very special lining to protect it. After the acid breaks down the food into chyme, it passes into the duodenum where the body has a phenomenal buffering system where it bathes the chyme is such a profoundly basic alkaline solution that ….
No need for you or anyone else to manipulate your dietary intake one way or another. There are plenty of good reasons for ensuring your diet includes critical basics like fats, proteins, sugars your brain lives on glucose alone, fyi , fibers, and a wide variety of nutrients and micronutrients and minerals.
Doctors do not give us squat to take orally to control our blood pH. Bc nothing taken orally can affect blood pH. When we are acidotic and at risk fo imminent death, drs give sodium bicarbonate thru an IV!! Diet does affect the function of your body. You are correct that the food you take in does not usually have a direct affect on your bodies function.
The critical part that most doctors leave out is how your diet affects your endocrine system, which controls your bodies function and its level of performance.
Typically foods with a higher ph support a healthier endocrine system. Not just because they are a higher ph, but because these food are more nutrient dense. The whole concept is to minimize toxins they have a huge negative affect on the endocrine system increase you nutrient intake to allow the endocrine system to get back in balance.
The hormones interact with each other at many different levels. There are no magic pills and not everything works exactly the same way for everyone.
Some conditions can not be corrected, but that does not mean to discard the Single most powerful treatment for all diseases. Yes, diet can affect health. I think you missed my point. Nutrition affects body function. Maintaining ph is part of body function. Nutrient dense foods tend to be more alkaline and thus help control and maintain normal healthy body function. Nutrition affects or activates proper hormone function and proper hormone function creates a healthy body. Poor nutrition or less nutrient dense foods create dysfunction and disease.
Theses foods tend to be more acidic and are not able to promote optimum health. That is a real stretch and is as ridiculous as claiming that plastic is natural because it comes from oil made by nature. Actually that is not true. The topic is blood pH regulation, which is carried out almost exclusively by respiration and kidney function. By the way did you ever stop and consider what many of those nutrients are?
For example ascorbic acid, folic acid, pantothenic acid, ascorbic acid, malic acid, chlorogenic acid, acidic polyphenols……….. Even beneficial fibers are fermented in a variety of health promoting acids. Yes, it is bunk. People are not using common sense or scientific facts and therefore are misinterpreting the study. What happens to the baking soda when it is ingested? Simple, it is neutralized by the stomach acid forming carbonic acid and sodium chloride salt.
So how is this supposedly helping to reduce acidity i the blood or muscles when it no longer has any buffering capacity? So why does it help?
Simple, the sodium chloride is an electrolyte, which can help increase endurance. I read that high acidity in body can cause cancer and so on… But when I read more about this, do not seem to be correct. So the next step was to Research about it more. Good and clear explanation. Thank you so much! The average and timing relative to digestion and other activity pH between highs and lows is more important….
And of course the body system is generally healthier when the average is mostly in alkaline status outside of increases when one eats a meal. Eating will increase acid level to help breakdown foods toward bioavailable components….. Basically a mix such as that is akin to putting cement or concrete into your systems, and the body tries to deal with this partly by increasing to more acidic levels As well as trying to tell us not to eat much processed food and such additives as calcium carbonate….
Tells us through various discomforts and difficulties as result. Craig, we are discussing blood pH, not the pH of the digestive system. What foods you eat does not affect your blood pH. Calcium carbonate reacts with stomach acid forming the absorbable salt calcium chloride.
Low Grade Chronic Metabolic Acidosis is real and it happens. Again, nobody claimed food does not affect your pH. Our blood pH is affected by diet since ALL foods metabolize in to acids, many of which are essential to our health, function and existence. Yes, it does and there are many reasons for this such as kidney or respiratory issues since there are the main means of pH regulation. Hi, What a load of tosh your article is.
I suffered from advanced prostate cancer which had become metastatic. Despite this, my psa started to rise dramatically from undetectable to 8. The future was bleak with the only real alternative being chemotherapy. After some research, I gave up all sugar which is highly acidic and hard cheese for the same reason and took baking soda every day. After an initial high dosage of up to three teaspoons a day in a glass of water, I now take a half teaspoonful in a glass of water morning and evening.
After three months, my psa had reduced to 2. I am off the hormonesand taking no other treatment and my oncologist has confirmed the reduction in psa is entirely of my own doing! Also, I have suffered with nasal polyps for 25 years and have had four operations to remove them. I have been told I am very good at growing nasal polyps and i would always have them and there is no known cause for them.
By now 6 years after my last operation i should be full of nasal polyps again, but guess what, I no longer have any nasal polyps. I have also lost about 8 pounds of belly fat and have more energy than I have had for years. But, I guess this is all a myth and I am dreaming!! His article demonstrates partial knowledge, which is even more useless than no knowledge at all. But your anecdote is still explained by the evidence Chris posted and numerous scientific studies that help us understand how cancer cells work.
Cutting all sugar out of your diet and focusing on a plant-heavy diet as Paleo thought leaders push time and again would obviously have a positive effect on your health. If you have an emotional tie to the acid-alkaline diet myth, then keep it. But looking down your nose at a man who has helped thousands overcome chronic disease that conventional medicine gave up on is arrogant and childish.
Caleb, food items are not considered acidic or alkaline. It is the metabolic effect that earns them the name acid or base forming. Sugar is considered acidic because it increase excretion of magnesium. ALL foods get metabolized in to acids. Proteins are broken down in to amino acids, then in to alkaline ammonia, which is then converted in to uric acid to protect the body from the highly alkaline and toxic ammonia.
Fats and oils are broken down in to fatty acids, which are then metabolized forming carbonic acid. Simple sugars are metabolized in to carbonic acid. Insoluble fibers are enzymatically broken down by the flora in to simple sugars that are then fermented forming a variety of beneficial acids. No, once again sugars are used as a fuel source and when broken down for energy we end up with the byproducts carbon dioxide and water forming carbonic acid, which is essential to many functions in the body.
No, lemons are considered acidic because if you test their pH they are acidic due to a variety of acids present such as citric acid, malic acid, oxalic acid, ascorbic acid, etc.
Unfortunately, I think most of you are off the mark. James had mentioned earlier how to explain chronic conditions such as: A person with asthma needs what? They all need O2. Without it, O2 can not be released to our tissues. Many of our chronic medical conditions are a result of or exasperated by our breathing, both at night during sleep and during the day. Lack of O2 creates a cascade of events that can explain virtually all of what James has stated. Let me share my experience. I am 44 years old male with type II diabetes and I have an intermission between jobs and skin dived spear fishing- apnea based for the last two months.
Here are the results. Increase muscle mass; much healthier eye lashes, nails, shiny skin, no sinus issues and no sinus related headaches. I become much more healthier in a period of three weeks. There is one trick though. I only got natural food during this time, which is also next to impossible in our urban prisons. That is not the correct answer. What was being referred to is what was missing that led to these diseases and conditions, which IS NOT oxygen.
If oxygen was missing then the cells would be dead, not in a disorder. But even with sufficient oxygen those diseases and conditions can still occur because oxygen is not the deficiency leading to those diseases and conditions. But you are correct about the CO2, or more specifically carbonic acid. The release of oxygen O2 from hemoglobin to tissues is dependent on carbonic acid.
This is why alkalinity inhibits oxygen release from hemoglobin decreasing tissue oxygenation. Lemons are not considered acidic because of the mineral profile. I did read the article. Apparently you did not read it yourself or you simply did not understand what it said. Additional buffering is contributed by the numerous histidine residues of hemoglobin and by plasma proteins.
Hmmm, no mention of acidifying or alkalizing minerals at all. Future therapies for treating bone loss disorders could be based on shifting systemic acid-base balance in the alkaline direction using diet e. Our findings also provide further rationale for the promotion of vascular health via aerobic exercise, avoidance of smoking, and good diet.
Then there are he conclusions of this study that show how diet is the cause of the many reasons for acidosis. But acidosis itself is super rare to begin with and acidosis severe enough to lead to bone loss is significantly more rare since buffering by bones is only used as a very last resort for pH buffering from the body. Why do you focus primarily on blood ph? The circulatory system is only one part of your body. You can not be objective if you do not look at the body as a whole being inside and out.
Nutrition is the key and more alkaline foods tend to be higher in the nutrients needed to keep the body healthy. A balance is important and promoting that it does not matter what you eat is irresponsible. The focus is on blood pH because when discussing the alkalize or die myth the alkalize refers to the blood, which is not affected by diet. In fact, many of these foods are highly acidic to begin with and ALL foods get metabolized in to acids.
So the article is discussing the myth that diet can alter blood pH for health. Again what is being pointed out is that it does not matter what you eat as far as blood pH goes since your pH IS NOT regulated by what you eat. But there is a major difference between affecting and regulating.
Will diet affect blood pH? Yes because ALL foods get metabolized in to acids. And without many of those acids we would not exist. But there is always too much of a good thing so those acids that affect the blood pH have to be regulated. It never once occurs to them that by taking charge of their WHOLE health and eating better as well as losing weight improves the naturally designed functions of your body… So it CAN fight off mutations and infections and long term damage.
We are trying to explain to people how the microscopic eggs that are laid in rotten food are connected to the larva worms which appear and later the bugs which soon will be seen surrounding the food source. And suddenly flies are born!!! As for why the author is focused on the blood pH…. The subject you are so sure you understand better than those educated in the science of bodily systems.
You are correct about the blood ph. I was only mentioning that the blood ph does not always control the ph of the body. Sometimes you have to look at the whole body and not just one area in question. Again when discussing the alkalize for health myth the reference is to blood pH, not the pH of other areas of the body, some of which that need to be acidic to be healthy.
The relationship between diet and cancer is well known. Dietary intake exists as the largest external or environmental epigenetic factor capable of driving the development or maintenance of cancer.
The American Institute for Cancer Research AICR comprehensive global report has compiled numerous studies demonstrating associations between dietary habits and cancer risk. The findings recommend increased or regular consumption of vegetables, fruits, whole grains, and legumes, while discouraging excess consumption of sugary and energy-dense foods and drinks, red and processed meats, and salty processed foods http: Acidity is a well known factor associated with cancer.
Lower pH levels in the extracellular space promote the invasive and metastatic potential of cancer cells. A net-acid diet or acidogenic diet is determined by the balance between acid and base-forming dietary constituents. Most fruits and vegetables are net-base producing foods since the metabolized products are organic anion precursors such as citrate, succinate, and conjugate bases of carboxylic acids. The conclusion of this study is relevant. It does not say Chronic Low Grade Metabolic Acidosis is a direct cause of cancer, but does conclude that it plays a role.
Blood PH is 7. Sugar is neutral at a pH of 7. Sugar is more acidic than blood. Secondly, a pH of 7 is neutral and thus not acidic. Lemons are acidic, right?
Jim Bagnall, Hi there, I too have metastatic prostate cancer, and am on the search for alternatives to chemo and hormone therapy.
I would appreciate any other information re your diet etc that you may be prepared to share. There are many different alternative therapies to treating a wide variety of different diseases. It is a serious condition and can not go untreated, if you are not willing to start traditional therapies, it would be in your best interest to see a Naturopathic Doctor who will be able to monitor you closely as even these natural remedies can have some nasty side effects if not followed closely.
There are many different vitamins and minerals that can be taken that have shown to be helpful in treating cancer patients. Before taking any supplementation though you need to either talk a doctor. It seems that no matter what people try to do to improve their health by alternative remedies or cures there will always be those that will attempt to dissuade them from doing so.
If one is stricken with a sickness or ailment that has been determined by doctors to be inoperable or curable, why would you not try an alternative? If traditional cures are not working then what have they got to lose by trying another form of treatment. I know I would do exactly the same if I were in this position. Investigations concerning Kupffer cells are hampered because in humans, Kupffer cells are only accessible for immunohistochemical analysis from biopsies or autopsies. From rats and mice, they are difficult to isolate, and after purification, only approximately 5 million cells can be obtained from one mouse.
Macrophages can express paracrine functions within organs that are specific to the function of that organ. In the testis for example, macrophages have been shown to be able to interact with Leydig cells by secreting hydroxycholesterol, an oxysterol that can be converted to testosterone by neighbouring Leydig cells.
Cardiac resident macrophages participate in electrical conduction via gap junction communication with cardiac myocytes.
Macrophages can be classified on basis of the fundamental function and activation. According to this grouping there are classically activated macrophages, wound-healing macrophages alternatively activated macrophages and regulatory macrophages Mregs. Macrophages that reside in adult healthy tissues either derive from circulating monocytes or are established before birth and then maintained during adult life independently of monocytes.
Monocytes are attracted to a damaged site by chemical substances through chemotaxis , triggered by a range of stimuli including damaged cells, pathogens and cytokines released by macrophages already at the site. At some sites such as the testis, macrophages have been shown to populate the organ through proliferation. Macrophages are professional phagocytes and are highly specialized in removal of dying or dead cells and cellular debris. This role is important in chronic inflammation, as the early stages of inflammation are dominated by neutrophils, which are ingested by macrophages if they come of age see CD31 for a description of this process.
The neutrophils are at first attracted to a site, where they proliferate, before they are phagocytized by the macrophages. The removal of dying cells is, to a greater extent, handled by fixed macrophages , which will stay at strategic locations such as the lungs, liver, neural tissue, bone, spleen and connective tissue, ingesting foreign materials such as pathogens and recruiting additional macrophages if needed.
When a macrophage ingests a pathogen, the pathogen becomes trapped in a phagosome, which then fuses with a lysosome.
Within the phagolysosome, enzymes and toxic peroxides digest the pathogen. However, some bacteria, such as Mycobacterium tuberculosis , have become resistant to these methods of digestion.
Typhoidal Salmonellae induce their own phagocytosis by host macrophages in vivo, and inhibit digestion by lysosomal action, thereby using macrophages for their own replication and causing macrophage apoptosis. Macrophages are versatile cells that play many roles. Along with dendritic cells , they are foremost among the cells that present antigens , a crucial role in initiating an immune response.
As secretory cells, monocytes and macrophages are vital to the regulation of immune responses and the development of inflammation; they produce a wide array of powerful chemical substances monokines including enzymes, complement proteins, and regulatory factors such as interleukin At the same time, they carry receptors for lymphokines that allow them to be "activated" into single-minded pursuit of microbes and tumour cells.
After digesting a pathogen, a macrophage will present the antigen a molecule, most often a protein found on the surface of the pathogen and used by the immune system for identification of the pathogen to the corresponding helper T cell.
The presentation is done by integrating it into the cell membrane and displaying it attached to an MHC class II molecule MHCII , indicating to other white blood cells that the macrophage is not a pathogen, despite having antigens on its surface. Eventually, the antigen presentation results in the production of antibodies that attach to the antigens of pathogens, making them easier for macrophages to adhere to with their cell membrane and phagocytose. In some cases, pathogens are very resistant to adhesion by the macrophages.
The antigen presentation on the surface of infected macrophages in the context of MHC class II in a lymph node stimulates TH1 type 1 helper T cells to proliferate mainly due to IL secretion from the macrophage. When a B-cell in the lymph node recognizes the same unprocessed surface antigen on the bacterium with its surface bound antibody, the antigen is endocytosed and processed. T cells that express the T cell receptor which recognizes the antigen-MHCII complex with co-stimulatory factors- CD40 and CD40L cause the B-cell to produce antibodies that help opsonisation of the antigen so that the bacteria can be better cleared by phagocytes.
Macrophages provide yet another line of defense against tumor cells and somatic cells infected with fungus or parasites. Once a T cell has recognized its particular antigen on the surface of an aberrant cell, the T cell becomes an activated effector cell, producing chemical mediators known as lymphokines that stimulate macrophages into a more aggressive form.
There are several activated forms of macrophages. M1 macrophages have pro-inflammatory, bactericidal, and phagocytic functions. M2 is the phenotype of resident tissue macrophages, and can be further elevated by IL Tumor-associated macrophages are mainly of the M2 phenotype, and seem to actively promote tumor growth.
Macrophages exist in a variety of phenotypes which are determined by the role they play in wound maturation. Phenotypes can be predominantly separated into two major categories; M1 and M2. M1 macrophages are activated by four key mediators: These mediator molecules create a pro-inflammatory response that in return produce pro-inflammatory cytokines like Interleukin-6 and TNF.
These cytokines are essential in the initial process of wound healing. M2 cells are divided into four major types based on their roles: M2a, M2b, M2c, and M2d.
How M2 phenotypes are determined is still up for discussion but studies have shown that their environment allows them to adjust to whichever phenotype is most appropriate to efficiently heal the wound. While M1 macrophages are the dominating phenotype observed in the early stages of inflammation, as the wound ages there is a significant decrease in M1 phenotype and an increase of M2 macrophages at the site.
If this shift failed to occur, there would be prolonged inflammation. M2 cells are needed for production of collagen at the wound site. They are needed for revascularization and reepithethelisation. It was previously thought that an increase of M2 macrophages may decrease the time it takes for wound closure. However, studies show that rate of wound closure is not affected by an increase in M2 cells. M2 macrophages are needed for vascular stability. This dysregulation results in insufficient M2 macrophages and its corresponding growth factors that aid in wound repair.
At this point, inflammation is not needed and M1 undergoes a switch to M2 anti-inflammatory. Both M1 and M2 macrophages play a role in promotion of atherosclerosis. The first step to understanding the importance of macrophages in muscle repair, growth, and regeneration is that there are two "waves" of macrophages with the onset of damageable muscle use — subpopulations that do and do not directly have an influence on repairing muscle.
The initial wave is a phagocytic population that comes along during periods of increased muscle use that are sufficient to cause muscle membrane lysis and membrane inflammation, which can enter and degrade the contents of injured muscle fibers.
These peak between two and four days and remain elevated for several days during the hopeful muscle rebuilding. It is thought that macrophages release soluble substances that influence the proliferation, differentiation, growth, repair, and regeneration of muscle, but at this time the factor that is produced to mediate these effects is unknown.
Macrophages are essential for wound healing. Once they are in the wound site, monocytes mature into macrophages. The spleen contains half the body's monocytes in reserve ready to be deployed to injured tissue.
The macrophage's main role is to phagocytize bacteria and damaged tissue,  and they also debride damaged tissue by releasing proteases. These factors attract cells involved in the proliferation stage of healing to the area. Scientists have elucidated that as well as eating up material debris, macrophages are involved in the typical limb regeneration in the salamander.
As described above, macrophages play a key role in removing dying or dead cells and cellular debris. Erythrocytes have a lifespan on average of days and so are constantly being destroyed by macrophages in the spleen and liver. Macrophages will also engulf macromolecules , and so play a key role in the pharmacokinetics of parenteral irons.