We are in no way affiliated with Costco in any way, shape, or form. In , the American College of Physicians 's guidelines were updated to recognize metformin as the first-line treatment for type-2 diabetes. Metformin is recommended to be temporarily discontinued before any radiographic study involving iodinated contrast agents, such as a contrast-enhanced CT scan or angiogram , as the contrast dye may temporarily impair kidney function, indirectly leading to lactic acidosis by causing retention of metformin in the body. This page was last edited on 13 September , at Retrieved October 26, through the Internet Archive. Archived from the original on May 4, Metformin or clomiphene are both first line treatments for infertility in women with PCOS.
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Where Does it Come From.